Acute cardiovascular responses to resistance exercise in anabolic steroids users: A preliminary investigation
2018
Summary Objectives Anabolic steroid (AS) use has increased in recent years, but the cardiovascular consequences for users is not fully understood. Equipment and Methods Resistance trained males (AS = 7, age = 29 ± 5; NAS = 6, age = 25 ± 1 yrs) undertook a resistance exercise session with echocardiographic measures and cardiac biomarkers taken pre and post exercise (cTnI, NT-proBNP). Results A significant decrease in early diastolic tissue velocity (E’) (AS = 13 ± 1 vs 11 ± 3, NAS = 13 ± 2 vs12 ± 1 cm.s −1 ), late diastolic tissue velocity (A’) (AS = 9 ± 2 vs 8 ± 1, NAS = 8 ± 1 vs 8 ± 1 cm.s −1 ), E’:A’ (AS = 1.63 vs 1.21, NAS = 1.71 vs 1.62) and E:A (AS = 1.61 vs 1.19, NAS = 1.63 vs 1.29) with an increase in late dia −1 ) were seen in both groups post-exercise. A significant decrease in left ventricular end-systolic volume (LVESV) (AS = 48 ± 16 vs 45 ± 12, NAS = 51 ± 9 vs 43 ± 11 ml) was seen post-exercise with maintenance of ejection fraction (EF). There was a significant group effect on diastolic blood pressure (BP) (AS = 74 ± 11 vs 66 ± 7, NAS = 68 ± 6 vs 58 ± 2 mmHg) and basal systolic rotation rate (AS = −61.69 ± 18.38 vs −86.65 ± 17.99, NAS = −63.69 ± 14.72 vs −56.50 ± 2.15 .s− 1 ). Conclusion Despite significant reductions in diastolic measures, with maintenance of systolic function, there was no altered cardiovascular response in the AS users following resistance exercise.
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