Discordance between fasting plasma glucose and A1c in the diagnosis and management of diabetes

There are pros and cons of using fasting plasma glucose (FPG) and A1c for the diagnosis and management of diabetes. Still, discordance between FPG and A1c is a common problem in clinical practice, and there are no definite international guidelines for dealing with it. This article explains the causes of these anomalies and the factors that affect the results of tests, and it also recommends some appropriate techniques for investigation and management of cases of discordance between FPG and A1c.