MICROVASCULAR ENDOTHELIAL FUNCTION DIFFERS BETWEEN HEART FAILURE WITH PRESERVED EJECTION FRACTION PHENOTYPES

Andreas B. Gevaert,Birgit Boehm,Flavia Baldassarri,Inge Goovaerts,Tibor Stoop,Haley Hartmann,Stephan Mueller,André Duvinage,Elisabeth Kraigher-Krainer,Caroline M. Van De Heyning,Paul Beckers,Ulrik Wisløff,Burkert Pieske,Ephraim B. Winzer,Martin Halle,Emeline M. Van Craenenbroeck,Optimex Investigators

MICROVASCULAR ENDOTHELIAL FUNCTION DIFFERS BETWEEN HEART FAILURE WITH PRESERVED EJECTION FRACTION PHENOTYPES

2019

Andreas B. Gevaert
Birgit Boehm
Flavia Baldassarri
Inge Goovaerts
Tibor Stoop
Haley Hartmann
Stephan Mueller
André Duvinage
Elisabeth Kraigher-Krainer
Caroline M. Van De Heyning
Paul Beckers
Ulrik Wisløff
Burkert Pieske
Ephraim B. Winzer
Martin Halle
Emeline M. Van Craenenbroeck
Optimex Investigators

Phenotypical heterogeneity among patients could be a reason why prognosis of heart failure with preserved ejection fraction (HFpEF) has not been improved in clinical trials. Vascular dysfunction is considered a central mediator in HFpEF pathophysiology, but its clinical detection has shown mixed

Keywords:

Pathophysiology
Clinical trial
Heart failure with preserved ejection fraction
Internal medicine
Phenotype
Cardiology
Medicine
Diabetes mellitus

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