Severe Hypouricemia Impairs Endothelium‐Dependent Vasodilatation and Reduces Blood Pressure in Healthy Young Men: A Randomized, Placebo‐Controlled, and Crossover Study

Benjamin De Becker,Catherine Coremans,Martin Chaumont,Cédric Delporte,Pierre Van Antwerpen,Thierry Franck,Alexandre Rousseau,Karim Zouaoui Boudjeltia,Pierre Cullus,Philippe Van De Borne

Severe Hypouricemia Impairs Endothelium‐Dependent Vasodilatation and Reduces Blood Pressure in Healthy Young Men: A Randomized, Placebo‐Controlled, and Crossover Study

2019

Benjamin De Becker
Catherine Coremans
Martin Chaumont
Cédric Delporte
Pierre Van Antwerpen
Thierry Franck
Alexandre Rousseau
Karim Zouaoui Boudjeltia
Pierre Cullus
Philippe Van De Borne

Background Uric acid (UA) is a plasmatic antioxidant that has possible effects on blood pressure. The effects of UA on endothelial function are unclear. We hypothesize that endothelial function is ...

Keywords:

Vasodilation
Internal medicine
Endothelium
Cardiology
Diabetes mellitus
Renin–angiotensin system
Hypouricemia
Crossover study
Uric acid
Blood pressure
Medicine
Febuxostat
Rasburicase
Endocrinology

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