Antipsychotic cardiomyopathy: to the problem of clinical diagnosis

Introduction The presented review is devoted to generalization of results of own researches of the author on a problem of almost not studied pathology ndash a neuroleptic antipsychotic cardiomyopathy NCMP NCMP belongs to secondary specific metabolic dilated cardiomyopathies It is caused by side cardiotoxic effect of antipsychotic preparations Many parties of epidemiology pathogenesis morphology clinic and diagnostics of NCMP remain still insufficiently developed Results As showed our researches the development of NCMP passes stages a latent b developed and c terminal Each stage has the clinical features and electrocardiograph signs The lethal outcome in latent and in developed stages either comes from the intercurrent diseases or is the sudden cardiac death of arhythmogenic genesis The progressing congestive heart failure serves in a terminal stage as an immediate cause of death Conclusion On the basis of synthesis of the data obtained in a number of the own researches clinical criteria of diagnostics of NCMP are allocated and proved Considering the described features of NCMP the given pathology is allocated in separate independent nosological unit expediently and quite logical