t cell-derived vaccines comprising an epitope between sequences that promote antigen presentation

Keep long chain peptide antigen having a plurality of epitopes, to provide an epitope between sequences which effectively induce antigen presentation of each epitope. In a vaccine having a long-chain peptide antigen having a plurality of epitopes, among the epitope sequences, 2 to 10 consecutive tyrosine, 2 to 10 consecutive threonine, 2 to ten consecutive alanine, achieved by 2 to 10 consecutive histidine, 2 to 10 amino vaccine, characterized in that the successive glutamine and 2 to 10 contiguous group consisting asparagine is one selected It is. The vaccine is preferably one selected from the group consisting of anti-cancer vaccines, antibacterial vaccines and antiviral vaccines. Also, vaccines, peptide vaccines, DNA vaccines, it is preferred mRNA vaccine is at least one of those selected from the group consisting of dendritic cell vaccines. .FIELD 1