Assesment of Single-Dipole and Dual-Dipole Inverse Solutions in Electrocardiography

In this study, we closely examined the performance of a well-known inverse solution in terms of equivalent dipole source model. To simulate potential distribution on the “body surface”, we employed an analytical model of a single current dipole (or a pair of current dipoles) placed within the homogeneous isotropic volume conductor consisting of two non-concentric spheres. Using these data, we evaluated the accuracy of recovering both location and orientation of the single or dual dipole sources. In total, we examined 24 different dipole locations and found that the location of both fitted single current dipoles and dual current dipoles virtually coincided with the original source for high S/N ratios. While our results corroborate findings obtained with more complex geometry, our tool provides an efficient and analytical means in assessing electrocardiographic inverse solutions.