Effect of mitomycin-c-assisted sutureless trabeculectomy on keratometry and axial length

Aim: Glaucoma is defined as chronic, progressive optic neuropathy caused by a group of ocular conditions, which leads to damage of the optic nerve with loss of visual function. This study was conducted to find out the changes in corneal curvature, axial length and intraocular pressure. Materials and Methods: The present study was conducted in the Department of Ophthalmology, S P Medical College and Associated Group of Hospitals, Bikaner. A total of fifty cases of either age- and sex-matched controls were selected for this study. These cases were divided into two groups: Group A (sutureless trabeculectomy with mitomycin-C [MMC]) and Group B (sutureless trabeculectomy without MMC). Results: The mean post-operative intraocular pressure (IOP) was lowered in MMC-treated eyes when compared to control at 1½ months. The IOP reduction was greater in the MMC-treated eyes (13.25 mmHg at 1½ months) as compared to control Group B (16.9 mmHg at 1½ months). Comparing results with the present study, it was found that success rate in MMC-treated eyes was noted in 23 (92%) individuals, in which complete success was in 22 (88%) while qualified success in 1 (4%) and qualified failure in 2 (8%) with mean IOP of 13.2 mmHg at 1½ months, whereas in control group, success rate was noted in 19 (76%) individuals, in which complete success was in 18 (72%) and qualified success in 1 (4%), while qualified failure in 6 (24%) with mean IOP of 16.9 mmHg at 1½ months after operation. Conclusion: Results of this study are in favour of intraoperative application of MMC during filtration surgery, especially in cases with high-risk failure.