A comparative study of intoxication severity in patients with acute purulent otitis media

: Plasma levels of medium molecular peptides (MMP) were measured and Paramecium test was made in 28 patients with acute otitis media purulenta (AOMP). Of these, 18 patients had complicating mastoiditis. The baseline results of both tests correlated with clinical symptoms of systemic endogenic intoxication. Paramecium test returned to normal after one day of treatment. Informative value of this test fell with detoxication contrary to plasma MMP value which correlated with the degree of intoxication and remained informative through detoxication being able to show even residual subclinical toxicity. The MMP test is a method of choice in assessing intoxication in patients with AOMP and its complications.