Long-term pulmonary sequelae of severe bronchopulmonary dysplasia.

Abstract Objective: To evaluate the long-term pulmonary sequelae of survivors of bronchopulmonary dysplasia (BPD) of sufficient severity to have required supplemental oxygen for at least 1 month after term. Study design: Fifteen patients with a mean age of 1.1 years were matched to preterm infants of similar gestational age and age at time of study. Pulmonary function testing included spirometry, plethysmographic lung volumes, carbon monoxide diffusion capacity, and in 9 of 15 subjects with BPD, measurement of lung static elastic recoil pressures. Results: The subjects with BPD had a mean expiratory volume in 1 second (FEV 1 ) of 64% ± 21% predicted (4 had an FEV 1 P P 1 and the time on supplemental oxygen ( r = –0.84, P 1 was Conclusion: Severe BPD may result in moderate to severe long-term abnormalities in pulmonary function tests. (J Pediatr 1998;133:193-200)