EVALUATION OF C-REACTIVE PROTEINS (CRP) IN THE DIAGNOSIS OF PREMATURE RUPTURE OF MEMBRANE IN PATIENTS ATTENDING IN TERTIARY CARE HOSPITAL AT MUZAFFARPUR, BIHAR

Objective:  C-Reactive Proteins (CRP) is an important marker of Sub-clinical infection in cases of Premature Rupture of Membrane (PROM).The aim of present study was the evaluation of CRP from the patients attending in our hospital with premature rupture of membrane. Materials and Method: A total of 32 patients of Preterm, Premature rupture of membranes and 32 patients preterm with intact membranes as a control, between 28-36 weeks of gestation were included in the study. Results: The Sensitivity and specificity of CRP determination was found to be 78.12% each as an early predictor of subclinical chorioamnionitis. TLC had a low sensitivity of 22% and specificity of 65% in detecting histological chorioamnionitis (HCA). Conclusion: CRP estimation is a simple, reliable, quite affordable and reasonably marker for the detection of early chorioamnionitis. Keywords: PROM, CRP, Chorioamnionitis, Sensitivity, Specificity