Association for Academic Surgery, 2004 Characterization of a Model to Independently Study Regression of Ventricular Hypertrophy 1,2

Conclusions. These results demonstrate a safe, effective, and reproducible method of promoting LVH regression—avoiding the need for endotracheal intubation, mechanical ventilation, and a second invasive surgery to remove the constriction. The simplicity of this technique combined with the well-known advantages of using the mouse species makes this model both unique and relevant. Ultimately, this model will facilitate focused study of independent mechanisms