Formation of immunity and tolerance to the cell membrane components in primary and secondary (postimplantation) cardiac immunopathies

: The role of humoral constituents of the innate immunity in altering of tolerance and formation of immune response to autoreactive cell membrane components during both primary endocardithis and atherosclerosis processes and secondary ones, following reconstructive implantation on heart was investigated. The ways of restoration of the tolerance to membrane components and elimination of immune deficiency during the treatment of primary and secondary immunopathy of the cardiovascular system before and after implantation were considered.