METHOD OF PRODUCING 2-(4-HYDROXYPHENYL)ETHANOL (n-THYROZOL)

FIELD: chemistry. SUBSTANCE: invention relates to a method of producing 2-(4-hydroxyphenyl)ethanol (p-thyrozol), having a marked stimulating effect, immunomodulating and cardioprotective activity, anticarcinogenic and anti-inflammatory properties. The method includes nitrating 2-phenylethanol, reducing 2-(4-nitrophehyl)nitroethanol and nitrating 2-(4-aminophenyl)ethanol with subsequent hydrolysis of the diazo-compound. Synthesis and hydrolysis of the diazo-compound is carried out in the presence of n-toluene sulphonic acid with molar ratio 2-(4-aminophenyl)ethanol:n-toluene sulphonic acid = 1.0:2.1-3.0. EFFECT: method enables to obtain an end product of high quality from affordable material without using hard-to-get and expensive reagents, as well as hazardous production processes. 2 tbl, 15 ex