A Comparative Analysis of Levels of FSH, LH, Testosterone, TSH, Oral Glucose Tolerance Test and Ultrasonography in Females with PCO, PCOS and Normal Control Cases from Industrial Town in Western India.

Incidence of anovulation showing PCOS in early age group (22-29 years) leading to problems like infertility, is rising progressively. High BMI and/or hirsutism is disturbing the psychology of early age educated girls. Association of changed lifestyle e.g. sedentary working pattens, lack of physical activities and changed eating habits are altering the HPO axis and Insulin functions. Present study was intended to find out and correlate altered biochemical markers with clinical presentations of the symptoms and polycystic appearance of ovaries on ultrasound, among women with PCOS, PCO and in women with other gyanecological complaints. 43 patients were included in PCOS group according to Rotterdams criteria, 16 in PCO group and 31patients were included as control group who presented with other gyanecological complaints. Clinical features on the basis of PCOS criteria including hirsutism, acne, obesity, infertility and oligomenorrhea were studied along with biochemical markers assessment of FSH, LH, TSH, Testosterone and OGTT. Hormonal milieu in normal weight and overweight/obese women differed in our study consistent with the findings of other studies. Further clinical studies with estimations of hormones associated with PCOS are required in Indian as well as other country women, to understand this complex interplay of different hormones.