Study of healthcare-associated infections in surgical unit in a newly established tertiary care hospital of Nanded, Maharashtra, India

Abstract Background Health care Associated Infections (HAI) has been responsible for the increasing cost, morbidity and mortality related to surgical Patients. Aim & objective(s) To Study bacteriological profile and its drug Sensitivity in a newly established hospital (after 1.5years) and to establish a data for future reference. Materials & methods Record based descriptive Study design conducted at Dr Shankarrao Chavan Government Medical College, Nanded, Maharshtra, India in month of July 2017. Total 2840 patients included in study admitted from October 2015 to March 2017 in surgical ward, Burn ward and Intensive care unit. Results The prevalence of HAI is 6.01%.The most frequent HAI were wound infections n = 44 (44.44%), urinary tract infections (UTI) n = 31 (31.31%), respiratory tract infections (RTI) 9%. Bacterial load was more in burn ward n = 51 (51.51%), SICU n = 36 (36.36%), General wards n = 15 (15.15%). The most common organism isolated was Pseudomonas sp n = 41 (41.41%) followed by E. coli n = 20 (20.20%), Klebsiella sp n = 11 (11.11%), Coagulase negative staphylococcus n = 8 (8%). Most species were resistant to Ciplofloxin, Gentamycin, Cefotaxim & cefazolin. Drugs Sensitivity of Enterobacteriaceae Sp is most commonly to Amikacin 28 (87.5),Cefoperazone + Sulbactum 11 (55),Piperacillin + Tazobactum 11 (65) Psudomonas spps more sensitive to Imipenam/Meropenam 38 (92%) becoming multidrug resistant to Piperacillin + Tazobactum, Cefoperazone + Sulbactum, Cefazolin. Conclusion The study underlined the role of Gram-negative bacteria in HAI. It also demonstrates the widespread problem of antibiotic resistance among nosocomial infections. Continued surveillance is necessary to guide appropriate empirical therapy for these infections.