Sequence of alkylation of cyclohexane-1, 3-dione. Alternative synthesis of (±)-Angustione
1991
A method is proposed for introducing one, two, or three alkyl substituents into positions 4 and 6 of the cyclohexane-1, 3-dione molecule by successive alkylation under the action of strong bases. (±)-Angustione (a natural β-diketone) has been synthesized.
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