The tyrosine kinase inhibitor genistein potentiates the antidiuretic effect of vasopressin and its analogs

: Genistein was shown to potentiate the effects of all the activators of the water flow except the cAMP action. The thyrosine kinase (TK) seems to suppress the hydrosmotic action of arginine vasopressin at the period preceding the cAMP formation and to potentiate this effect afterwards.