Enantioselective Copper‐Catalyzed 1,4‐Addition of Dialkylzincs to Enones Using a Novel N,N,P‐Cu(II) Complex.

Abstract Enantioselective copper-catalyzed 1,4-additions of dialkylzincs to enones were carried out in the presence of 1 mol % of Cu(OTf) 2 and 2.5 mol % of an N,N,P -ligand possessing a tert -butyl group at the adjacent position of the nitrogen of pyridine to afford the corresponding 1,4-adducts in up to 98% ee.