The Effect of Caffeine on p53-Dependent Radioresponses in Undifferentiated Mouse Embryonal Carcinoma Cells after X-ray and UV-irradiations

Department of Late Effect Studies and Department of System Biology, Radiation Biology Center, Kyoto University, Yoshida Konoe, Sakyo-ku, Kyoto 606–8501, Japan Department of Science for Laboratory Animal Experimentation, Research Institute for Microbial Diseases, Osaka University, Yamadaoka 3–1, Suita, Osaka 536– 0871, Japan Department of Morphogenesis, Institute of Molecular Embryology and Genetics, School of Medicine, Kumamoto University, Kuhonji 4–24–1, Kumamoto 862– 0976, Japan Department of Molecular and Cell Genetics, School of Life Sciences, Faculty of Medicine, Tottori University, Nishimachi 86, Yonago, Tottori 683–8503, Japan (Received, June 12, 2000) (Revision received, June 30, 2000) (Accepted, July 4, 2000)