Clinical analysis of Candida albicans infection in acute exacerbations of Chronic obstructive pulmonary disease

Objective To find out the risk factors in lung infection,clinical features and therapeutic of candida albicans infection in acute exacerbations of chronic obstructive pulmonary disease.Methods 50 cases of AECOPD with Candida albicans infection were retrospectively analyzed,comparing with 50 cases without fungal infection.The risk factors in lung infection,clinical features and therapeutic of Candida albicans infection were analyzed and calculated.The former for the test group,the latter as a control group.Results The average age of the patients in the test group,was 66.6 years old,75% of total cases were in the merger of consciousness,serum albumin lower than 28 g/L( 50% ),average usage time of antibiotics more than 14 days (75 % ),glucocorticoid was used significantly higher than control group (83.3%).Conclusion If the merger of consciousness,low serum albumin,antimicrobial drug use is too long,the glucocorticoids used in patients with AECOPD,candida albicans infection were increased,but the age and sex had no impactiou obviously.The patients with basic diseases such as diabetes,cardiovascular and cerebrovascular disease,cancer,malignancy or chronic renal insufficiency were combined with high rates of candida albicans infection. Key words: Chronic obstructive pulmonary disease;  Candida albicans;  Infection;  Risk factors