An In Vitro Model for Studying Interactions Between Mouse Trophoblast and Uterine Epithelial Cells

Even a cursory examination of the published attempts to devise an in vitro implantation system for mammalian embryos reveals that there have been two distinct approaches (Table I). One approach involves the use of complex tissues to mimic as closely as possible the natural conditions of the embryo or invasive cells. The other approach uses single cells in order to identify specific cellular and molecular events.