Study on optimization of synthesis conditions of chloromethylation reagent (BCMB) by orthogonal method

The chloromethylation reagent1,4-bis(chloromethoxyl) butaneas(BCMB) is synthesized with l,4-butyl glycol as a raw material,through homogeneous.The product is characterized by infrared spectroscopy(IR).Orthogonal experimental method is used to obtain the optimal reaction time,temperature,and the ratio solvent to material.The suitable condition of synthesis is as follows:reaction time 4 hours,temperature is 20 degrees Celsius,the ratio of liquid to material 3:1.The yield is about 80%