GASTRORETENTIVE DRUG DELIVERY SYSTEMS: NOVEL APPROACHES AND ITS EVALUATION - A REVIEW Review Article

There are different types of dosage forms, which are being administered through different routes. However oral route is the most preferred route of administration because of its patient compliance. Now days, oral controlled release systems are designed offering a number of advantages including improvement in patient compliance, therapeutic efficacy and safety. Gastric retention time is one of the important factors, which adversely affect the performance of these drugs when administered simply by an oral controlled drug delivery system. The purpose of this review is to provide complete information on the gastroretentive drug delivery systems (GRDDS) such as role and properties of gastrointestinal (GI) tract, factors affecting the gastric retention time, classification of gastroretentive dosage form and its evaluation parameters.