Growth Hormone Receptor Gene Polymorphism and its Associations with Some Growth traits in West-Azarbaijan Native chicken

The chicken growth hormone (GHR) gene has an important function in chicken growth and reproduction. Polymorphisms (are the most frequently found DNA sequence variations in the animal genome and can be used as genetic markers for association analysis with economic traits. The primary aim of this study was to identify polymorphisms in GHR as potential candidate genes for growth and production traits in Iranian chicken. In this study 200 blood samples were collected form West-Azarbaijan Native chicken (100 hens and 100 roosters) to investigate GHR gene polymorphism using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). According to the data, HindIII was able to produce 2 final alleles: A and B. the A allele was in 290 and 428 bases while B allele located in 170, 258 and 290 bases. Also, AA genotype was in 290 and 428 bases whereas BB founded in 170, 258 and 290 bases, respectably. Furthermore, in this study no heterozygote identified. Mutation on AA genotype was in the 294 nucleotide. Also, the observed mutation for BB genotype located in the 541 nucleotide. In both genotypes the mutation