AB0561 Prevalence and Clinical Manifestation of Deforming Arthropathy in Thai Patients with Systemic Lupus Erythematosus

Background Articular manifestation in systemic lupus erythematosus (SLE) is common and can range from arthralgia to chronic erosive deforming arthropathy. Objectives This study was performed to determine the prevalence, clinical features, and serological findings in Thai SLE patients with deforming arthropathy. Methods All SLE patients seen at the Rheumatology Clinic, Chiang Mai University Hospital, between January and December 2012, were included in this study. Their medical records were reviewed, together with a review of their history and physical examination, with special attention paid to the articular system. Those patients with evidence of hand arthropathy were invited to join the study. The arthropathy was classified according to van Vugt9s classification. Results Forty of 458 SLE patients (8.7%) had deforming arthropathy. Their mean ± SD age and disease duration were 34.5±14.7 years and 8.8±7.5 years, respectively. There were erosive arthritis with 13 (2.8%) cases, Jaccoud9s arthropathy with 8 (1.7%), and mild deforming arthropathy with 19 (4.1%). Of these 40 patients, 23 (57.5%) were diagnosed rheumatoid arthritis (RA) with a mean duration of 7.5±8.9 years before the SLE diagnosis was made. Discoid rashes were significantly more common in the mild deforming arthropathy group (63.2%) than in the erosive arthritis group (7.7%) and the Jaccoud9s arthropathy group (0.0%), p Conclusions Deforming arthropathy is not uncommon in Thai patients with SLE, and shares similar clinical features to those previously reported. Disclosure of Interest None declared DOI 10.1136/annrheumdis-2014-eular.2936