The clinical analysis of Menetrier disease

Objective To investigate the clinical features of Menetrier disease and the related treatment progresses. Methods The clinical data of 7 patients with Menetrier disease who were admitted to Cangzhou Central Hospital from Jan 1997 to Mar 2018 were retrospectively analyzed. Results There were 3 males and 4 females. The main clinical manifestations were abdominal pain (n=5), loss of appetite (n=4), nausea and vomiting (n=2), weight loss (n=4), edema (n=3), hypoalbuminemia (n=6) and anemia (n=6). All patients had typical imaging findings. Two of the patients underwent non-surgical treatmen with temporary symptom reliefs. Finally, 6 patients received surgical treatment including Subtotal gastrectomy in 1 patient, total gastrectomy in 5 patients. All the 6 cases underwent surgery successfully with no serious complications. 5 cases were followed-up data until April 2018. All were in good condition, Hemoglobin and albumin levels were within the normal range. Conclusion According to the clinical manifestations and the related auxiliary examinations, this disease is easy to diagnose. Surgical treatment is the only way to cure Menetrier disease. Key words: Gastritis, hypertrophic; Surgical procedures, operative