Montmorillonite Powder Combined with Vitamin B_6 for Azithromycin-induced Adverse Reactions of Gastrointestinal Tract:Clinical Randomized Control Trials
2009
OBJECTIVE:To evaluate the efficacy of combined use of montmorillonite powder and vitamin B6 to attenuate azithromycin-induced adverse reactions of gastrointestinal tract. METHODS: 103 patients with respiratory infection in the outpatient pediactric department treated with azithromycin were enrolled: 53 cases (treatment group) received montmorillonite powder plus vitamin B6 additionally,and 50 cases(control group) were not given montmorillonite powder and vitamin B6. RESULTS: The incidence of adverse reaction of gastrointestinal tract was 15.1% for treatment group versus 48.0% for control group,showing significant differences between the two groups(χ2=95.025,P0.01). CONCLUSION: Montmorillonite powder combined with vitamin B6 showed satisfactory curative efficacy for azithromycin-induced adverse reactions of gastrointestinal tract.
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