MicroRNAs as potential biomarkers for noninvasive detection of fetal trisomy 21

Ji Hyae Lim,Da Eun Lee,Shin-Young Kim,Hyun Jin Kim,Kyeong Sun Kim,You Jung Han,Min-Hyoung Kim,Jun Seek Choi,Moon-Young Kim,Hyun Mee Ryu,So Yeon Park

MicroRNAs as potential biomarkers for noninvasive detection of fetal trisomy 21

2015

Ji Hyae Lim
Da Eun Lee
Shin-Young Kim
Hyun Jin Kim
Kyeong Sun Kim
You Jung Han
Min-Hyoung Kim
Jun Seek Choi
Moon-Young Kim
Hyun Mee Ryu
So Yeon Park

Purpose The objective of this study was to discover a panel of microRNAs (miRNAs) as potential biomarkers for noninvasive prenatal testing (NIPT) of trisomy 21 (T21) and to predict the biological functions of identified biomarkers using bioinformatics tools.

Keywords:

Internal medicine
Gene expression profiling
Endocrinology
Fetus
Down syndrome
microRNA
Prenatal diagnosis
Biology
Trisomy
Biomarker (medicine)
Cancer research
Genetics
Pregnancy
Bioinformatics
Human genetics
potential biomarkers
Obstetrics

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