Arterial coronary revascularization failure as a result of coronary vasospasm
2008
Discussion Although this experience is limited to a single case, a low-dose rt-PA regimen with longer infusion duration is a promising approach for patients who are in hemodynamically stable condition and do not require rapid lysis. There may be a lower complication rate because of the significantly lower infusion rate, despite longer infusion duration. Patients should be monitored closely for adequate lysis. This includes daily echocardiography and laboratory evaluations (D-dimer, activated partial thromboplastin time, and fibrinogen). Fluoroscopy should be used to confirm leaflet motion. Further investigation is necessary to evaluate the shortand long-term efficacy and safety of this treatment strategy.
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