Su1969 Comparison of H. pylori Infection, Clinicopathologic Findings and Molecular Pathology Between Young and Old Gastric Cancer Patients

lower 65 (30.1%); Period II: upper 37 (20.0%), middle 85 (45.9%), lower 61 (33.0%), Period III: upper 35 (22.2%), middle (40.5%), lower 55 (35.9%). Pathological examination revealed as follows (differentiated type/ undifferentiated/ others/ unknown); Period I: 132/ 69/0/17; Period II: 123/54/2/6; Period III: 103/43/2/0. These data indicated the locations and pathological features of the stomach cancer in this survey were not changed in recent 10 years. Regarding therapeutic approach to gastric cancer, open laparotomy was mainly applied to the gastric cancer in period I (2002-2004) as 159 out of 216 (73.6%) patients. Endoscopic treatment was performed in 38 patients (17.6%), whereas only 4 patients (1.9%) were treated under laparoscopy. In Period II (2005-2007), the ratio endoscopic treatment increased significantly (24.3%, 45/153). The ratio of laparoscopic surgery increased form 1.9% to 13.0% (24/153), although the number of gastric cancer patients treated by open laparotomy was decreased (58.9% 109/185). In Period III, the ratio of laparoscopic surgery (32.0% 49/153) was markedly increased compared to Periods I & II, while increase in the ratio of endoscopic treatment was limited (52/153 34.0%). because application of endoscopic treatment was limited to the gastric cancer within themucosa. This study clearly demonstrated therapeutic approach to the gastric cancer was replaced open laparotomy with endoscopic treatment and laparoscopic surgery in recent 10 years, although backgrounds of the gastric cancer were not changed.