Association of Glycated Hemoglobin and Dyslipidemia Inpatients with Type 2 Diabetes Mellitus in a K.M.C.H. Katihar, Bihar-A Retrospective, Cross-Sectional and Descriptive Study

Introduction: Dyslipidemia is one of the major risk factors for cardiovascular disease in diabetesmellitusType2.The aim of the study was to understand the pattern of dyslipidemia and its association withglycated hemoglobin (HBA1C) among Type 2 diabetic.Materials and Methods: This was a retrospective cross-sectional study to assess the relationship betweenglycemic control (as reflected by HBA1C) and serum lipid profile in Type2 diabetic patients which includeda total of 200 Type2 diabetic patients (104 males; 96 females; mean age years 62.91). Venous blood sampleswere collected from all the patients after at least 8 h fasting.Results: HBA1C, fasting blood glucose (FBG), total cholesterol, triglycerides (TG), high-density lipoprotein(HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol were analyzed. In male and femalepatient, serum levels of HBA1C, FBG, and LDL were not significantly different. As compared to males,female patients showed significantly higher serum cholesterol and HDL but significantly lower TG levels.Correlation between HBA1C and FBG was highly significant in this study. Both HBA1C and FBG exhibiteddirect correlations with cholesterol, TG, and LDL and inverse correlation with HDL; the magnitude ofsignificance for all these lipid parameters being greater with HBAIC than FBG. There was a linearrelationship between HBA1C and dyslipidemia. The levels of serum cholesterol and TG were significantlyhigher and of HDL significantly lower in patients with worse glycemic control as compared to patients withgood glycemic control.Conclusion: The findings of this study clearly showed that HBA1C is not only a useful biomarker of longtermglycemic control but also a good predictor of lipid profile.