TCT-444 Left Ventricular Thinning and Distension to Mimic Heart Failure and Functional Mitral Regurgitation in Swine Hearts: A Platform to Test New Transcatheter Mitral and Heart Failure Devices

The need for clinically relevant experimental platforms of functional mitral regurgitation (FMR) are necessary to test new transcatheter mitral valve devices. Isolated mitral valve models of FMR have been reported previously, but they lack a left ventricle (LV). This study reports a novel model of