Telmisartan-amlodipine rapid-release tablet and preparation method thereof
2017
The invention provides a telmisartan-amlodipine rapid-release tablet. The telmisartan-amlodipine rapid-release tablet comprises a telmisartan layer, an isolation layer and an amlodipine layer, wherein (a) the telmisartan layer contains telmisartan solid dispersion, meglumine, a filler, a disintegrant and a lubricating agent; (b) the isolation layer contains starch, dextrin, ethyecellulose and a lubricating agent; (c) the amlodipine layer contains benzenesulfonate amlodipine micro powder, a filler, a disintegrant and a lubricating agent. The tablet can rapidly release telmisartan and benzenesulfonate amlodipine at the same time, and has high storage stability.
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