A Review on Acatalasemia

Catalase deficiency, also known as acatalasemia, is a disease marked by abnormally low levels of the enzyme catalase. Many individuals with acatalasemia have never had any health issues and are now diagnosed because they have affected family members. Some of the first people diagnosed with acatalasemia developed open sores (ulcers) within their mouths, resulting in soft tissue death (gangrene). Takahara disease is a disorder that occurs when acatalasemia causes mouth ulcers and gangrene. Because of changes in oral hygiene, these complications are rarely seen in more recent cases of acatalasemia. According to studies, people with acatalasemia are more likely to develop type 2 diabetes, which is the most common type of diabetes. Type 2 diabetes affects a higher proportion of people with acatalasemia than the general population, and the disorder strikes at a younger age. Acatalasemia may also be a risk factor for other common, complex diseases, according to researchers.