Hormone sensitive lipase inhibition by selected medicinal plants

extracts. These active plants are Malva nicaeensis All. (IC 50 = 51.07 µg/ml), Haplophyllum buxbaumii (Poir.) G. Don. (101.3 µg/ml), Anchusa italica Retz. (132.8 µg/ml), Cleome africana Botsch. (168.9 µg/ml), Salvia fruticosa Mill. (276.7 µg/ml), Glaucium aleppicum Boiss. and Hausskn. ex Boiss. (289.7 µg/ml), Reseda alba L. (396.6 µg/ml), Mentha spicata L. (421.3 µg/ml), Ononis natrix L. (422.8 µg/ml), Chrysanthemum coronarium L. (463.7 µg/ml), Anagallis arvensis L. (751.9 µg/ml), and Hypericum triquetrifolium Turra (828.6 µg/ml). The extracts of the majority of other tested plants showed, however, moderate to weak activities. The results of the present screening provide good herbal choices to combat insulin resistance in human, thus playing a role in developing successful herbal remedies for diabetes and related disorders.