Correlation Of Ocular Perfusion Pressure And Ocular Pulse Amplitude In Glaucoma, Ocular Hypertensive And Normal Individuals

Purpose: To investigate a possible correlation between ocular perfusion pressure (OPP) and ocular pulse amplitude (OPA) in individuals with glaucoma, ocular hypertension and normals. Methods: Ninety eyes from 90 patients were selected in which: 30 were recently diagnosed with glaucoma before starting any ocular hypotensive medications, 30 had elevated intraocular pressure (IOP>mention the number) without any evidence of glaucoma, and 30 were included in the control group with normal IOP and without any evidence of glaucoma. They underwent Goldmann applantion tonometry, dymanic contour tonometry (Pascal), blood pressure (BP), pachymetry, Humphrey visual field (except the control group), and routine ophthalmologic examination. The OPP was calculated by the difference between mean arterial blood pressure and IOP. The OPA was measured by the Pascal tonometer. Results: Mean OPA in the glaucoma group was 3.4 ± 1.2 mmHg, ocular hypertensive 3.5 ± 1.2 mmHg, and normals 2.6 ± 0.9 mmHg. Mean OPP was 46.3 ± 7.9 mmHg in the glaucoma group, 46.3 ± 7.9 mmHg in the ocular hypertensive, and 50.2 ± 7.0 mmHg in the normals. Neither groups showed significant correlation (p-value > 0.05) between OPP and OPA. Pearson coefficient test was used for corelation between glaucoma and ocular hypertensive groups , while Spearman’s rank coefficient correlation was used to test for the normal group. Conclusions: OPP and OPA values do not correlate with each other in individuals with glaucoma, ocular hypertensive and normals.