Electrochemical studies of dopamine in presence of uric acid and hydroquinone at TiO 2 nanoparticles: a voltammetric study

Commercially available titanium oxide nanoparticles (TiO2NPs) and its stable sensitive voltammetric determination of dopamine in the presence of uric acid and hydroquinone was studied by cyclic voltammetric and differential pulse voltammetric technique. TiO2NPs was characterized by using scanning electron microscopy (SEM), transmission electron microscope (TEM), X-ray diffraction (XRD), and infrared spectroscopy (IR).The TiO2NPs modified carbon paste electrode (TiO2NPs/MCPE) shows excellent electrochemical enhancement of peak currents for dopamine. The detection limit for dopamine was determined from a differential pulse voltammetric technique was found to be 3.6 × 10−8 M and quantification limit was 12.8 × 10−8 M. The interference studies reveal that the TiO2NPs/MCPE exhibits an excellent selectivity towards dopamine in the presence of large excess of uric acid and hydroquinone. From the concentration study, the oxidation of dopamine was found to be adsorption controlled. The use of TiO2NPs/MCPE is demonstrated for the detection of dopamine in blood serum and injection samples.