Study on the medication program of antibiotics preventing puerperal infection after cesarean section

OBJECTIVE To explore a better therapeutic regimen of antibiotics preventing puerperal infection after cesarean section,and to provide references for clinical information and reduce the rate of puerperal infection. METHODS From Dec.2011to May 2012,412cases of cesarean section patients in our hospital were selected as the subjects of study,and were divided into three groups in accordance with different therapeutic regimens,140 cases in group A were treated with cefathiamidine,124cases in group B were treated with cefmetazole,148cases in group C were treated with ceftezole,then compared the clinical effect of the regimens in three groups. RESULTS The puerperal infection rate of group B was 11.3%,which was significantly higher than group A(2.9%)and group C(4.1%),the difference was statistically significant(P0.05);However,the difference of postoperative morbidity in the three groups had no statistical significance;the temperature recovery time of group C was significantly shorter than group A and B,and the difference was statistically significant(P0.05);the difference of hospitalization time in the three groups had no statistical significance;the sequence of treatment costs were group Agroup Cgroup B.CONCLUSION Clinicians should select economic and effective postoperative antibiotics to prevent puerperal infection after cesarean section in accordance with the condition of patients,and to ensure the life safety of patients.