OROFACIAL FOREIGN BODY REACTION TO COSMETIC MATERIAL: REPORT OF 3 NEW CASES

Orofacial foreign body reactions are adverse effects to cosmetic fillers that are often used for esthetic purpose. Case 1 involved a 76-year-old woman with a painless swelling in the upper lip lasting 1 year. Case 2 involved a 53-year-old woman presenting multiple painless normal-colored nodules of unknown duration located in the lower lip mucosa. Case 3 involved a 77-year-old woman with a painless nodule in the right buccal mucosa of unknown duration. All patients admitted having undergone a cosmetic procedure in the past. Microscopically, all cases showed variable-sized empty microcysts, surrounded by a mixture of histiocytes, collagen bundles, multinucleated giant cells, and inflammatory cells. Patients are under follow-up after treatment that consisted of surgical excision of the material. Foreign body reactions to cosmetic fillers are uncommon in the orofacial region.