Abstract 12168: Risk Stratification for Ventricular Tachyarrhythmias in Patients With Cardiac Sarcoidosis by Cardiac Magnetic Resonance Imaging

Introduction: Recently, late gadolinium-enhancement (LGE) cardiac magnetic resonance (CMR) imaging, which has been used to uniquely characterize the myocardial fibrosis, is reported to have a prognostic value in cardiac sarcoidosis (CS) Hypothesis: Not only fibrosis mass, but also its localization may help to identify the risk of ventricular tachyarrhythmias (VA) in patients with CS. Methods: 70 consecutive CS patients underwent CMR (cine and LGE imaging). Left ventricular (LV) mass and fibrosis mass were calculated and the localization was analyzed using 17 segment model. VA was defined as sustained ventricular beats ≥ 3 or ventricular fibrillation. The patients underwent prospective follow-up through 2015 from CMR examinations. Results: 33.3 % of the patients had a history of VA at the time of CMR examination. During a median follow-up of 15.5 months, 31.9 % had new-onset (11.6 %) or recurrent VA (20.3 %). Increased LV fibrosis mass (LVFM) was associated with the prevalence of VA (P < 0.001) and receive...