Fast CW imager for ICG and Gd kinetics

Gadolinium (Gd) pharmacokinetics are useful in diagnosis of breast cancer with MRI; previous work has suggested that the pharmacokinetics of indocyanine green (ICG) may prove to be similarly useful in optical mammography. Here, we describe a fast optical imaging device to acquire images of ICG kinetics simultaneously with Gd kinetics and coregister the images. This direct comparison between the widely accepted Gd diagnostic techniques and optical methods is essential for clinical acceptance of optical techniques by the radiological community.