Mismatch repair deficiency testing for immune checkpoint therapy: Immunohistochemistry vs microsatellite instability.

Sucha Sudarsanam,Forrest Blocker,Sally Agersborg,Vincent Funari,Shiping Jiang,Wayne Chen,J. W. Ragheb,Vladislav Chizhevsky,Maher Albitar

Mismatch repair deficiency testing for immune checkpoint therapy: Immunohistochemistry vs microsatellite instability.

2018

Sucha Sudarsanam
Forrest Blocker
Sally Agersborg
Vincent Funari
Shiping Jiang
Wayne Chen
J. W. Ragheb
Vladislav Chizhevsky
Maher Albitar

3022Background: DNA mismatch repair deficiency (dMMR) can be tested by immunohistochemistry (IHC) or microsatellite instability (MSI). While either IHC and MSI is adequate for establishing Lynch sy...

Keywords:

MISMATCH REPAIR DEFICIENCY
Pathology
Cancer research
Medicine
Immune checkpoint
Microsatellite instability
Immunohistochemistry
DNA mismatch repair

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