ABO, H, Lewis and Secretor histo-blood group-like carbohydrates in pathogenic and non-pathogenic invertebrates
2019
ABO, H, Lewis, and Secretor histo-blood group systems express a repertoire of carbohydrate antigens in
human hematopoietic and non-hematopoietic tissues. The oligosaccharide components of these systems are
widely distributed in nature, including animal and plants. A set of reports demonstrated that pathogenic and
non-pathogenic invertebrates are able to synthesize and or acquire histo-blood group-like carbohydrates
from hosts. These abilities seem to be related to strategies for cell invasion as well as scape from host’s
innate and adaptive immune responses. This text revised the literature and offers a tentative explanation for
the presence of histo-blood group-like carbohydrates in pathogenic and non-pathogenic invertebrates and
its importance in terms of evolution.
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