Association of MBL2 gene exon 1 variants with autoimmune thyroid disease in Brazilian patients.
2012
Summary
We investigated the association between MBL2 gene exon 1 functional polymorphisms and autoimmune thyroid disease (AITD) in 163 Brazilian patients (87 with Hashimoto thyroiditis, HT; 76 with Graves’ disease) and 214 healthy controls. Individuals carrying MBL2 O allele are at higher risk of developing AITD (OR = 1.58, 95% CI: 1.11–2.26; P-value = 0.009) and HT (OR = 1.67, 95% CI: 1.09–2.55; P-value = 0.013) as suggesting a possible role for mannose-binding lectin in influencing disease susceptibility.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
19
References
3
Citations
NaN
KQI