Response to Comment on “The Common R71H-G230A-R293Q Human TMEM173 Is a Null Allele”

In their “Letter to the Editor,” Sivick et al. ([1][1]) disputed our results and conclusion. They claimed human R71H-G230A-R293Q ( HAQ ) STING is “fully functional . ” We stand by our results and conclusion. Below are our responses to their comments. ### Human PBMC studies In contrast to