Applications of Functionalized Quantum Dots in Tumor in vivo Imaging

The quantum dots(QDs) will have biological function by surface modification with biomolecules or drug molecules. The functionalized QDs have been widely applied in biomedical optical diagnosis and therapy for their unique optical propriety and biocompatibility. This paper introduced the synthesis and modification methods of functionalized QDs, and summarized their applications for tumor in vivo diagnosis and therapy, including in vivo lymph node imaging, blood vessel dynamic imaging, tumor imaging and anti-tumor drug tracking, et al.Finally, we also discussed the perspective and the challenge of the functionalized QDs utilization for the tumor in vivo diagnosis and therapy.