Peculiarities of pregnancy course and pregnancy outcomes in tobacco smoking

Tobacco is an urgent problem in Russia and in the world. Recent years have seen increased prevalence of smoking among the population. Tobacco dependence is included in the international classification of diseases, the American Psychiatric Association. From habit associated increase in the frequency of chronic diseases, mortality. In Russia smokes about 30 % of women and half of them continue to smoke during pregnancy. Proved that chronic nicotine intoxication has a negative effect on the pregnancy and fetus, worsens perinatal outcomes. It is also known that when tobacco smoking increases the level of homocysteine in the body, which in turn have toxic effects on vasculature. With many gestational hyperhomocysteinemia associated complications (gestoses, placental insufficiency, miscarriage and other). Already, there are methods of prevention and treatment of hyperhomocysteinemia. However, studies on folate metabolism in pregnant smoking a little. No clear approaches to the maintenance and inspection of this group of patients. I would like to draw attention to the state of folate metabolism in pregnant women with nicotine intoxication, reveal features of pregnancy, methods of prevention and treatment of gestational complications.