Single-Port versus Multi-Port Robot-Assisted Radical Prostatectomy: A Propensity Score Matching Comparative Study.

PURPOSE To compare the perioperative outcomes of patients who underwent single-port (SP) robot-assisted radical prostatectomy (RARP) and those who underwent multi-port (MP)-RARP. METHODS Data on 40 consecutive patients who underwent SP-RARP between June 2020 and February 2021 and 129 who underwent MP-RARP between June 2019 and February 2021 were retrospectively reviewed. Using logistic regression, 31 patients who underwent SP-RARP were matched to 31 patients who underwent MP-RARP (1:1) based on propensity scores. The available perioperative parameters and outcomes were analyzed. RESULTS Compared to MP-RARP, SP-RARP showed no significant differences in perioperative parameters, including the console times (111.0±15.7 vs. 102.6±18.8 minutes, p=0.569), operation time (151.3±15.1 vs. 158.7±20.3 minutes, p=0.863), estimated blood loss (121.1±64.7 vs. 140.5±90.5 mL, p=0.638), positive surgical margins (19.4% in both groups), and 3-month continence (77.4% vs. 83.9%, p=0.563) and potency (45.2% vs. 48.4%, p=0.891) rates. Patients who underwent SP-RARP had lower proportions of complete nerve sparing than those who underwent MP-RARP (SP-RARP vs. MP-RARP in subjective scores: 4.0±0.8 vs. 4.4±0.9, p=0.046; SP-RARP vs. MP-RARP in pathologic score of 5, 35.5% vs. 64.5%, p=0.049; score of 4, 41.9% vs. 19.4%, p=0.038; score of 3, 19.4% vs. 9.7%, p=0.398; score of 2, 3.2% vs. 0.0%, p=0.365; and score of 1, 3.2% vs. 3.2%, p=0.932, respectively). CONCLUSIONS SP-RARP showed lower nerve sparing scores than MP-RARP, the present study suggests that SP-RARP is safe and feasible with comparable short-term functional outcomes as those of MP-RARP.