Human vaginal fluid contains exosomes that have an inhibitory effect on an early step of the HIV-1 life cycle

Objective:Vaginal transmission is crucial to the spread of HIV-1 around the world. It is not yet clear what type (s) of innate defenses against HIV-1 infection are present in the vagina. Here, we aimed to determine whether human vaginal fluid contains exosomes that may possess anti-HIV-1 activity.Me